Las Vegas Raiders (4-4) at San Francisco 49ers (6-1): prediction and pick

San Francisco 49ers are clear favorites at 80% to win (SF -9.5). Our predicted score is Las Vegas Raiders 21, San Francisco 49ers 31, against a betting total of 51.5. San Francisco 49ers come in hot, 4-1 in their last 5. Las Vegas Raiders come in cold, 1-4 in their last 5. Las Vegas Raiders have 4 players listed out or doubtful. Check the final injury report before betting.

Fair odds: Las Vegas Raiders +400, San Francisco 49ers -400. Built from the betting line with the sportsbook's cut removed.

Predicted score: Las Vegas Raiders 21, San Francisco 49ers 31

Spread: SF -9.5

Total: 51.5

Moneyline: Las Vegas Raiders +380, San Francisco 49ers -500

DraftKings line. Shop around, prices differ by book.

• San Francisco 49ers: 4-1 in the last 5 (L W W W W, most recent first)
• Las Vegas Raiders: 1-4 in the last 5 (W L L L L, most recent first)

San Francisco 49ers: Marques Sigle (Questionable), Garret Wallow (Questionable), Luke Gifford (Questionable), Upton Stout (Questionable), Nick Bosa (Questionable)

Las Vegas Raiders: Darien Porter (Questionable), Malik Benson (Out), Dont'e Thornton Jr. (Out), Aidan O'Connell (Out), JJ Pegues (Out)

Check again close to game time.

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